Economics of Treatment and Prevention Services for Drug & Alcohol Abuse (R21)



The National Institutes of Health (NIH), a part of the U.S. Department of Health and Human Services, is the primary Federal agency for conducting and supporting medical research. Composed of 27 Institutes and Centers (ICs) the NIH provides leadership and financial support to researchers in every state and throughout the world.

This Funding Opportunity Announcement (FOA) issued by the National Institute on Drug Abuse (NIDA) and the National Institute on Alcohol Abuse and Alcoholism (NIAAA) encourages Research Project Grant (R21) applications on the economics of prevention and treatment services for drug and alcohol abuse. Such research projects might emphasize any of the following subjects: (1) financing and purchasing of drug and alcohol treatment and prevention services, including studies of health insurance and payment mechanisms; (2) economic incentives used to improve the quality and economic efficiency of treatment and prevention services (3) alternative delivery systems and managed care; (4) cost-benefit, cost-effectiveness, or cost-utility analyses; (5) service costs, production, and economic efficiency; and (6) research to develop or improve methods to be used in the economic study of drug and alcohol services.

This FOA will use the NIH Exploratory/Developmental (R21) grant mechanism and runs in parallel with two FOAs of identical scientific scope, PA-08-174 and PA-08-172, that solicit applications under the R01 and R03 mechanisms, respectively.

Note: applications submitted under R21 mechanism should be exploratory and novel. These studies should break new ground or extend previous discoveries toward new directions or applications. For example, long-term projects, or projects designed to increase knowledge in a well-established area will not be considered for R21 awards. See details in NIH Exploratory/Developmental Research Grant Award (R21).

Data Limite

New Applications Submission Date(s): closed.
AIDS and AIDS-Related Applications: Sep 7, 2011.


    1. Several of the steps of the registration process could take four weeks or more;
    2. On time submission requires that applications be successfully submitted no later than 5:00p.m. local time (of the applicant institution/organization).

Eligible Individuals: any individual with the skills, knowledge, and resources necessary to carry out the proposed research are invited to work with their institution/organization to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH support.

Applicants may submit more than one application, provided that each application is scientifically distinct.

Note: foreign Applications [Non-domestic (non-U.S.) Entity)] must indicate how the proposed project has specific relevance to the mission and objectives of the IC and has the potential for significantly advancing the health sciences in the United States.

Valor Financiado

Budget and Project Period: the total project period for an application submitted in response to this funding opportunity may not exceed two years. Direct costs are limited to US$275,000 over an R21 two-year period, with no more than US$200,000 in direct costs allowed in any single year.

Foreign applicants must complete and submit detailed budget requests using the R & R Budget component found in the application package. See NOT-OD-05-004.

Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. Although the financial plans of the Institutes and Centers (ICs) provide support for this program, awards pursuant to this funding opportunity are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications.


NIH policies concerning grants to foreign (non-U.S.) organizations can be found in the NIH Grants Policy Statement. Applications from foreign organizations must:

  1. Request budgets in U.S. dollars;

  2. Prepare detailed budgets for all applications (that is, complete the Research & Related Budget component of the SF424 (R&R) application forms. See also NOT-OD-06-096;

  3. Charge back of customs and import fees is not allowed;

  4. Format: Every effort should be made to comply with the format specifications, which are based upon a standard U.S. paper size of 8.5″ x 11″ within each PDF;

  5. Funds for up to 8% administrative costs (excluding equipment) may be requested. See NOT-OD-01-028;

  6. Organizations must comply with Federal/NIH policies on human subjects, animals, and biohazards;

  7. Organizations must comply with Federal/NIH biosafety and biosecurity regulations. See Section VI.2., “Administrative and National Policy Requirements”.

Forma de Solicitação

A one-time registration is required for institutions/organizations at both and eRA Commons. All registration formalities must be completed prior to submission. For details, please refer to the following documents: NIH eRA Commons System (COM) Users Guide, Prepare to Apply, Registration Instructions for Domestic and Foreign Organizations, and NIH eSubmission Tips for International Applicants.

Prepare all applications using the SF424 (R&R) application forms and in accordance with the SF424 (R&R) Application Guide for this FOA. The Application Instructions and the Application Package are available at Apply for Grant Electronically. A letter of intent is not required for the funding opportunity.

The SF424 (R&R) Application Guide is critical to submitting a complete and accurate application to NIH. There are fields within the SF424 (R&R) application components that, although not marked as mandatory, are required by NIH (e.g., the “Credential” log-in field of the “Research & Related Senior/Key Person Profile” component must contain the PD/PI’s assigned eRA Commons User ID). Agency-specific instructions for such fields are clearly identified in the Application Guide. For additional information, see “Frequently Asked Questions - Application Guide, Electronic Submission of Grant Applications.”

See Section IV.1 for details about application materials.


The NIH encourages inquiries concerning this funding opportunity and welcomes the opportunity to answer questions from potential applicants. Inquiries may fall into three areas: scientific/research, peer review, and financial or grants management issues. See details on the link Agency Contacts.

Direct questions regarding registration to Customer Support or email Direct questions regarding the Commons registration to eRA Commons Help Desk or email

Home Page


As informações descritas acima foram obtidas na home page da Financiadora.

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